MT-ND5 ELISA Kit for Human(Homo sapiens) | EIAab.comMT-ND5 ELISA Kit for Human(Homo sapiens)

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MT-ND5 (Gene name),

NADH-ubiquinone oxidoreductase chain 5 (Protein name ), NU5M_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MT-ND5(MTND5;NADH5;ND5);

Protein name:

NADH-ubiquinone oxidoreductase chain 5;

Alternative:

NADH dehydrogenase subunit 5;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular Location:

Mitochondrion inner membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

603

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

603:

LIT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF06455

KEGG:

hsa:4540

SMR:

P03915

MIM:

252010

String:

P03915

Uniprot:

P03915

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ELISA Kit for Human NADH-ubiquinone oxidoreductase chain 5

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E2000h

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ELISA Kit for Human NADH-ubiquinone oxidoreductase chain 5

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E2000p

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96T

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ELISA Kit for Human NADH-ubiquinone oxidoreductase chain 5

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E2000b

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96T

ELISA Kit for Human NADH-ubiquinone oxidoreductase chain 5

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E2000d

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96T

ELISA Kit for Human NADH-ubiquinone oxidoreductase chain 5

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E2000c

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ELISA Kit for Human NADH-ubiquinone oxidoreductase chain 5

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CLIA Kit for Human NADH-ubiquinone oxidoreductase chain 5

Cat.:

U2000p

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96T

CLIA Kit for Human NADH-ubiquinone oxidoreductase chain 5

Cat.:

U2000b

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96T

CLIA Kit for Human NADH-ubiquinone oxidoreductase chain 5

MSDS:

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CLIA Kit for Human NADH-ubiquinone oxidoreductase chain 5

Cat.:

U2000c

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96T

CLIA Kit for Human NADH-ubiquinone oxidoreductase chain 5

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U2000d

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96T

CLIA Kit for Human NADH-ubiquinone oxidoreductase chain 5

Cat.:

U2000h

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Polyclonal Antibody for Human NADH-ubiquinone oxidoreductase chain 5

Cat.:

P2000Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human NADH-ubiquinone oxidoreductase chain 5

Monoclonal Antibody for Human NADH-ubiquinone oxidoreductase chain 5

Protein for Human NADH-ubiquinone oxidoreductase chain 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Sequence and organization of the human mitochondrial genome."
Anderson S. , Bankier A.T. , Barrell B.G. , de Bruijn M.H.L. , Coulson A.R. , Drouin J. , Eperon I.C. , Nierlich D.P. , Roe B.A. , Sanger F. , Schreier P.H. , Smith A.J.H. , Staden R. , Young I.G.
Nature290:457-465(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

Kogelnik A. , Brown M.
Submitted (1997-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 456
3.

"Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs."
Horai S. , Hayasaka K. , Kondo R. , Tsugane K. , Takahata N.
Proc. Natl. Acad. Sci. U.S.A.92:532-536(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS PRO-211; VAL-257 AND VAL-314
tissue: Placenta.
4.

"Major genomic mitochondrial lineages delineate early human expansions."
Maca-Meyer N. , Gonzalez A.M. , Larruga J.M. , Flores C. , Cabrera V.M.
BMC Genet.2:13-13(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT VAL-257
5.

"Lineage-specific selection in human mtDNA: lack of polymorphisms in a segment of MTND5 gene in haplogroup J."
Moilanen J.S. , Finnila S. , Majamaa K.
Mol. Biol. Evol.20:2132-2142(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Mitochondrial genome variation and the origin of modern humans."
Ingman M. , Kaessmann H. , Paeaebo S. , Gyllensten U.
Nature408:708-713(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines."
Ingman M. , Gyllensten U.
Genome Res.13:1600-1606(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
8.

"Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians."
Coble M.D. , Just R.S. , O'Callaghan J.E. , Letmanyi I.H. , Peterson C.T. , Irwin J.A. , Parsons T.J.
Int. J. Legal Med.118:137-146(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
9.

"Mitochondrial DNA sequences of primates: tempo and mode of evolution."
Brown W.M. , Prager E.M. , Wang A. , Wilson A.C.
J. Mol. Evol.18:225-239(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-79
10.

"Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase."
Chomyn A. , Mariottini P. , Cleeter M.W.J. , Ragan C.I. , Matsuno-Yagi A. , Hatefi Y. , Doolittle R.F. , Attardi G.
Nature314:592-597(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF PROTEIN
11.

"The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification."
Murray J. , Zhang B. , Taylor S.W. , Oglesbee D. , Fahy E. , Marusich M.F. , Ghosh S.S. , Capaldi R.A.
J. Biol. Chem.278:13619-13622(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY
12.

"Normal variants of human mitochondrial DNA and translation products: the building of a reference data base."
Marzuki S. , Noer A.S. , Lertrit P. , Thyagarajan D. , Kapsa R. , Utthanaphol P. , Byrne E.
Hum. Genet.88:139-145(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SER-17; SER-95; PRO-99; ASP-146; VAL-160; SER-165; SER-304; ALA-331 AND GLY-503
13.

"Mitochondrial DNA complex I and III mutations associated with Leber's hereditary optic neuropathy."
Brown M.D. , Voljavec A.S. , Lott M.T. , Torroni A. , Yang C.C. , Wallace D.C.
Genetics130:163-173(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LHON THR-458
14.

"Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathy."
Johns D.R. , Berman J.
Biochem. Biophys. Res. Commun.174:1324-1330(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LHON THR-458
15.

"When does bilateral optic atrophy become Leber hereditary optic neuropathy?"
Howell N. , Halvorson S. , Burns J. , McCullough D.A. , Poulton J.
Am. J. Hum. Genet.53:959-963(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LHON GLU-465
16.

"Identification of a novel mutation in the mtDNA ND5 gene associated with MELAS."
Santorelli F.M. , Tanji K. , Kulikova R. , Shanske S. , Vilarinho L. , Hays A.P. , DiMauro S.
Biochem. Biophys. Res. Commun.238:326-328(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MELAS ASN-393
17.

"Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome."
Rieder M.J. , Taylor S.L. , Tobe V.O. , Nickerson D.A.
Nucleic Acids Res.26:967-973(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-475
18.

"Leigh disease associated with a novel mitochondrial DNA ND5 mutation."
Taylor R.W. , Morris A.A.M. , Hutchinson M. , Turnbull D.M.
Eur. J. Hum. Genet.10:141-144(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LS LEU-124
19.

"Is the mitochondrial complex I ND5 gene a hot-spot for MELAS causing mutations?"
Liolitsa D. , Rahman S. , Benton S. , Carr L.J. , Hanna M.G.
Ann. Neurol.53:128-132(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MELAS GLY-145 AND LEU-237
20.

"A missense mutation in the mitochondrial ND5 gene associated with a Leigh-MELAS overlap syndrome."
Crimi M. , Galbiati S. , Moroni I. , Bordoni A. , Perini M.P. , Lamantea E. , Sciacco M. , Zeviani M. , Biunno I. , Moggio M. , Scarlato G. , Comi G.P.
Neurology60:1857-1861(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LS CYS-250
21.

"The role of the ND5 gene in LHON: characterization of a new, heteroplasmic LHON mutation."
Mayorov V. , Biousse V. , Newman N.J. , Brown M.D.
Ann. Neurol.58:807-811(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LHON VAL-171
22.

"Novel mitochondrial DNA ND5 mutation in a patient with clinical features of MELAS and MERRF."
Naini A.B. , Lu J. , Kaufmann P. , Bernstein R.A. , Mancuso M. , Bonilla E. , Hirano M. , DiMauro S.
Arch. Neurol.62:473-476(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MELAS THR-236
23.

"Mutations in the ND5 subunit of complex I of the mitochondrial DNA are a frequent cause of oxidative phosphorylation disease."
Blok M.J. , Spruijt L. , de Coo I.F.M. , Schoonderwoerd K. , Hendrickx A. , Smeets H.J.
J. Med. Genet.44:E74-E74(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LS THR-236;VARIANT MELAS ASN-393
24.

"High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency."
Calvo S.E. , Tucker E.J. , Compton A.G. , Kirby D.M. , Crawford G. , Burtt N.P. , Rivas M. , Guiducci C. , Bruno D.L. , Goldberger O.A. , Redman M.C. , Wiltshire E. , Wilson C.J. , Altshuler D. , Gabriel S.B. , Daly M.J. , Thorburn D.R. , Mootha V.K.
Nat. Genet.42:851-858(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MT-C1D LEU-124; ALA-253 AND ASN-393;VARIANT SER-447

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